Abstract: Objective: To analyze the acupoint selection patterns of acupoint catgut embedding therapy in the treatment of polycystic ovary syndrome (PCOS) over the past 20 years based on data mining. Methods: Clinical research literature on acupoint catgut embedding therapy for PCOS was retrieved from databases including China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform (Wanfang),China Science and Technology Journal Database (VIP),and China Biology Medicine disc (CBM),with the search period from April 1, 2005 to April 1, 2025. Acupoint catgut embedding therapy prescriptions were summarized and a database was established. SPSS26.0, SPSS Modeler18.0, and Excel were used for acupoint frequency statistics, as well as association rule analysis and cluster analysis. Results: A total of 71 articles were included, yielding 71 acupoint prescriptions involving 48 acupoints, with a cumulative acupoint citation frequency of 662 times. The top 6 most frequently used acupoints in acupoint catgut embedding therapy for PCOS were Guanyuan (CV4),Tianshu (ST25), Sanyinjiao (SP6),Fenglong (ST40),Zhongwan (CV12),and Zusanli (ST36). The most commonly used meridians were the conception vessel and the stomach meridian of foot-yangming. Among specific acupoints,front-mu points and back-shu points were most frequently selected, followed by five-shu points, eight influential points, lower he-sea points, luo-connecting points, eight confluent points, xi-cleft points, and yuan-primary points. The main therapy was acupoint catgut embedding combined with Chinese medicine. Association rule analysis of high-frequency acupoints identified "Tianshu (ST25)- Fenglong (ST40)-Zusanli (ST36)" as the core acupoint pair. Cluster analysis divided the acupoints into three clusters: Cluster A included Pishu (BL20), Yinlingquan (SP9), Shuifen (CV9), Fenglong (ST40),Zusanli (ST36),Sanyinjiao (SP6),Guanyuan (CV4),Zhongji (CV3),and Daimai (GB26); Cluster B included Zhongwan( CV12),Daheng( SP15),and Shuidao( ST28);Cluster C included Tianshu( ST25), Qihai (CV6), Zigong (EX-CA1), and Xuehai (SP10). Conclusion: The acupoint selection for acupoint catgut embedding therapy in the treatment of PCOS is diverse, primarily focusing on Tianshu (ST25), Fenglong (ST40), and specific acupoints. The therapeutic approach predominantly emphasizes regulating and harmonizing the zang-fu organs.