Abstract: Atopic dermatitis (AD) falls into the categories of cubito-popliteal eczema and eczema in traditional Chinese medicine (TCM). Its prolonged course and refractory nature align with the TCM theories that "undiagnosed diseases are often caused by phlegm" and "prolonged illnesses often involve blood stasis. " Professor SUI Daoshun proposes that AD is characterised by a syndrome of deficiency in the root and excess in superficiality. The recurrent attacks and intractable, thickened skin lesions are not solely due to pathogenic exuberance but arise from the intertwining of healthy qi deficiency with pathological products such as phlegm and stasis. In the early stage, AD is characterized by root deficiency, with phlegm and stasis gradually generated. As the condition persists, pathogenic factors linger,and phlegm and stasis become mutually intermingled. Over time,a kennang (encysted accumulation of phlegm and blood stasis) forms,deeply latent in the collateral vessels. Therefore,the core pathogenesis of AD lies in the formation of "kennang" due to the intermingling of phlegm and stasis. The treatment should focus on resolving phlegm,eliminating stasis,tonifying deficiency,and cultivating the vital essence. The application of modified Guizhi Fuling Pills can achieve certain therapeutic effects.