基于“六郁”学说探讨自身免疫性脑炎的辨治

Exploration of Diagnosis and Treatment of Autoimmune Encephalitis Based on Theory of "Six Constraints"

摘要:

基于“六郁”学说探讨自身免疫性脑炎（AE） 的病机与治疗，认为AE核心病机为“郁滞窍闭”，即气机郁滞，进而引发湿、痰、热、血、食诸郁交织，最终导致清窍蒙蔽、神明惑乱。据此提出以“开郁通窍”为治疗总纲，前驱期以疏肝解郁为主，急性期侧重化湿、涤痰、清热，恢复期重在活血化瘀，全程兼顾消食导滞、调畅脾胃，为AE的临床治疗提供参考。

Abstract:

Abstract： Based on the theory of "six constraints， " this study explores the pathogenesis and treatment of autoimmune encephalitis （AE）. The core pathogenesis of AE is believed to be "constraint obstructing the orifices， " where qi constraint leads to intertwined dampness，phlegm，heat，blood，and food constraints，ultimately resulting in clouding of the clear orifices and mental confusion. Accordingly， the overarching treatment principle proposed is "relieving constraint to unblock the orifices." The prodromal stage focuses on soothing the liver and relieving constraint， the acute stage emphasizes resolving dampness， dispelling phlegm， and clearing heat， and the recovery stage prioritizes promoting blood circulation and resolving stasis. Throughout the treatment，attention is also paid to promoting digestion and regulating the spleen and stomach. This approach provides a reference for the clinical treatment of AE.