基于温病伏邪理论探析EB病毒感染导致鼻咽癌的病机及治疗思路

Pathogenesis and Therapeutic Strategies of Epstein-Barr Virus Infection-Associated Nasopharyngeal Carcinoma from Warm Disease Latent Pathogen Theory

摘要:

鼻咽癌是EB病毒感染、饮食、体质等多方面因素共同作用的结果，EB病毒感染作为鼻咽癌发病的首要因素，其隐匿性、伺机发病、易于化热等表现可归属于中医温病伏邪范畴。文章基于温病伏邪理论，认为正虚邪犯是EB病毒诱发鼻咽癌的根本原因，病机为本虚标实，兼夹湿、热、毒、痰、瘀等致病因素，最后发展成为鼻咽癌，以清热滋阴、扶正祛邪为治疗原则。通过对温病伏邪的进一步挖掘及应用，为中医药辨治鼻咽癌提供新思路。

Abstract:

Abstract：Nasopharyngeal carcinoma results from a combination of factors，including Epstein-Barr virus （EBV） infection， dietary habits， and constitutional predisposition. As the primary contributing factor， EBV infection， with its characteristics of latency，opportunistic onset，and tendency to transform into heat，can be categorized under the concept of latent pathogens in warm disease theory in traditional Chinese medicine. Based on the theory of latent pathogens in warm diseases，this article posits that deficiency of healthy qi and invasion by pathogens constitute the root cause of EBV-induced nasopharyngeal carcinoma. The fundamental nature of the disease is root deficiency with branch excess， accompanied by pathogenic factors such as dampness， heat， toxicity， phlegm， and stasis， ultimately leading to the development of nasopharyngeal carcinoma. Accordingly，the basic therapeutic principle of clearing heat and nourishing yin，supporting healthy qi and eliminating pathogens is summarized. By further exploring and applying the concept of latent pathogens in warm diseases，this study aims to provide new perspectives for the differentiation and treatment of nasopharyngeal carcinoma in traditional Chinese medicine.