基于文献分析中医药治疗岭南地区高血压病的用药规律

Analysis of Medication Patterns in Traditional Chinese Medicine for Hypertension in the Lingnan Region Based on Literature Review

摘要:

目的：基于中医传承计算平台整合中国知网、万方、维普数据库2000—2025年发表的关于中医药 治疗岭南地区高血压病的文献，分析其用药规律和组方特点，为临床实践提供循证依据。方法：检索中医药治 疗岭南地区高血压病的相关文献，筛选后通过中医传承计算平台V3.5进行药物频次、性味归经统计及关联规 则、聚类分析。结果：共纳入59篇文献，包含91首处方，205味中药。高频药物为茯苓、甘草、天麻、白术、 陈皮；药性以寒、平、温为主；药味以甘、苦、辛居多；归经以肝、脾、肺为主。药物功效主要以补虚、清 热、利水渗湿、平肝息风为主。关联规则显示核心药对为茯苓-白术、天麻-钩藤、茯苓-陈皮等。通过Kmeans 聚类分析得到4个处方核心组合。结论：中医药治疗岭南地区高血压病以健脾祛湿、化痰平肝为核心， 兼顾补虚与清热，体现因地因人制宜特色。

Abstract:

Abstract： Objective： To integrate and analyze the medication patterns and prescription characteristics of traditional Chinese medicine for hypertension in the Lingnan region over the past 25 years （2000-2025） using the Traditional Chinese Medicine Inheritance Computing System （TCMICS），based on databases such as CNKI，Wanfang， and VIP，in order to provide evidence-based support for clinical practice. Methods：Literature related to hypertension in the Lingnan region was retrieved and screened. The TCMICS V3.5 was utilized to analyze drug frequency，properties， flavors， meridian tropism， association rule analysis， and cluster analysis. Results： A total of 59 articles were included， comprising 91 prescriptions and 205 Chinese medicinal herbs. The most frequently used herbs were Poria， Glycyrrhizae Radix et Rhizoma， Gastrodiae Rhizoma， Atractylodis Macrocephalae Rhizoma， and Citri Reticulatae Pericarpium. The primary herb properties were cold， neutral， and warm， with sweet， bitter， and pungent as the predominant flavors. The meridians most commonly targeted were the liver， spleen， and lung. The main therapeutic effects included tonifying deficiency， clearing heat， promoting diuresis and percolating dampness， and calming the liver to extinguish wind. Association rules identified core herb pairs such as Poria-Atractylodis Macrocephalae Rhizoma， Gastrodiae Rhizoma-Uncariae Ramulus cum Uncis， Poria-Citri Reticulatae Pericarpium. K-means cluster analysis yielded four associated prescriptions. Conclusion： The traditional Chinese medicine treatment of hypertension in the Lingnan region focuses on fortifying the spleen，dispelling dampness，resolving phlegm，and calming the liver，while also tonifying deficiency and clearing heat. This reflects the principle of tailoring treatment to local conditions and individual characteristics.